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J Alzheimers Dis ; 84(4): 1447-1452, 2021.
Article in English | MEDLINE | ID: covidwho-1485013

ABSTRACT

Previous studies have identified dementia as a risk factor for death from coronavirus disease 2019 (COVID-19). However, it is unclear whether Alzheimer's disease (AD) is an independent risk factor for COVID-19 case fatality rate. In a retrospective cohort study, we identified 387,841 COVID-19 patients through TriNetX. After adjusting for demographics and comorbidities, we found that AD patients had higher odds of dying from COVID-19 compared to patients without AD (Odds Ratio: 1.20, 95%confidence interval: 1.09-1.32, p < 0.001). Interestingly, we did not observe increased mortality from COVID-19 among patients with vascular dementia. These data are relevant to the evolving COVID-19 pandemic.


Subject(s)
Alzheimer Disease , COVID-19 , Alzheimer Disease/complications , Alzheimer Disease/mortality , COVID-19/complications , COVID-19/mortality , Dementia, Vascular/complications , Humans , Retrospective Studies , Risk Factors
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